Amicus Therapeutics Fighting Rare and Orphan Diseases with Relentless Research

Based in Cranbury, New Jersey, Amicus Therapeutics, is a biopharmaceutical company that develops therapeutics for rare and orphan diseases that are called lysosomal storage disorders.

Their platform, CHART, focuses on developing of enzyme replacement therapies with which to treat these lysosomal disorders. They are known in the biopharmaceutical industry as having an abundance of small molecule pharmacological chaperones.

As Amicus Therapeutics does not have the capability of manufacturing their products on their own they must rely on contracting it to other manufacturers, such as JCR Pharmaceutical and GlaxoSmithKline. They worked with them from 2010 to 2013 in investigating the coformulation and recombinant alpha-galactosidase for the advancement of migalastat monotherapy.

Amicus Therapeutics expanded its research facility from New Jersey, opening a second research site in San Diego, California in 2008 (Yahoo Finance). Then in 2010, they were able to collaborate with David Geffen at the School of Medicine,UCLA due to a grant received for $500,000 from the Michael J. Fox Foundation, the same year they received another grant for $210,300 from the Alzheimer’s Drug Discovery Foundation for pre-clinical research with Ichan School of Medicine, Mount Sinai, working with the Alzheimer’s Disease Research Center.

In 2013, a competitor of Amicus, Callidus Biopharma was acquired which gained them intellectual property and proprietary access for an enzyme replacement treatment for Pompe disease, an inherited Lysosomal Storage Disorder caused by the body not producing the enzyme acid alpha-glucosidase or GAA.

Their leading product, migalastat, which is used to treat persons with Fabry disease,a disease that can lead to progressive and irreversible organ damage. This disease will affect the nervous system as well as cardiac, renal and a multitude of other tissues. Migalastat is in the late stages of development.

Amicus has built a belief statement to cover their core values plus be a reminder for the reason they do every day what they do. Part of the belief is that they believe in the fight against these diseases, they strive to have the highest quality therapies for anyone with these diseases. They firmly believe in supporting the communities of these diseases and their families.
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Dr. Richard Shinto and Penelope Kokkinides: Leading InnovaCare Health

InnovaCare Health is a recognized name in the market of health services in North America, specifically in Puerto Rico. This institution has done significant progress over the years and now has the honour of being one of the most renowned providers of managed healthcare services. There are two main avenues of care through which care is provided to the clients, including Medicaid Programs, Medicare Advantage, and Provider Networks. Moreover, InnovaCare Health strives to renovate and bring revolution in the field of healthcare management in order to meet the requirements of the people and provide facilities that are according to the international standards. This medical health care institution always makes sure that patients are prioritized and the relation with them is valued.

No organization can influence the market and be successful among strong competitors without having a clear set of values that would dictate the course of its journey. These values include providing top-notch medical and health care and making patients a top priority. Furthermore, they also make sure that their management team exceeds expectations and keeps up the values of transparency and quality. InnovaCare Health has also enriched the values of corporate integrity, teamwork, problem-solving via communication, experienced leadership, and achieving goals with substantial outcomes.

InnovaCare Health would not have been on the path of success and amongst leading healthcare providers without the efforts of its visionary leadership and team. Dr. Richard Shinto is the President and Chief Executive Officer of InnovaCare, Inc. His 20 years of experience in healthcare makes him a valuable asset to the leadership. Dr. Shinto has also worked as Chief Medical Officer of NAMM California. He has also remained the president and Chief Executive Officer of Aveta Inc. until 2012. Dr. Richard Shinto received his Bachelor’s degree from the University of California at Irvine, and later went to the State University of New York at Stony Brook for his medical degree. Dr. Shinto also has an MBA from the University of Redlands.

Another noteworthy name that is part of InnovaCare, Inc. is Penelope Kokkinides. She is appointed as the Chief Administrative Officer at InnovaCare, Inc. Kokkinides has more than 20 years of experience in medical healthcare, making clinical programs, and managing health care procedures with emphasis on improving infrastructure. Before this, Kokkinides served as the Executive Vice President and Chief Operating Officer at Centerlight HealthCare. Recently, three new experts have joined the leadership board of InnovaCare, Inc., which include Jonathan Meyers, Mike Sortino, and Penelope Kokkinides. All of the personnel mentioned above are expected to contribute to the success of InnovaCare, Inc. with their expertise, high level of experience, and professional skills. Read more about the interview of Penelope in Ideamensch.

Competitors are Trying to Steal the Success of NutriMost

NutriMost is suing a competing company called Healthy Living for stealing one of its promotional videos. The video was formally on the NutriMost website, but was allegedly stolen and placed on, which is the site belonging to Healthy Living.

 Weight loss company Nutrimost files lawsuit against rival Healthy Living for allegedly stealing promotional video

While the video was kept mostly intact when placed on Healthy Living’s website, including testimonials for NutriMost, the video replaced mention of Nutrimost with Can’t Lose Diet references.

According to court papers filed in Manhattan Federal Court, Healthy Living didn’t remove the video after receiving a cease-and-desist letter from NutriMost. Instead of removing the video, they simply replaced it with a shorter version.

NutriMost is seeking a court order that will force Healthy Living to pay $300,000 and keep them from posting the video again. NutriMost is demanding that amount due to the theft, but also the loss of their reputation.

The Nutrimost program involves eating organically, which keeps harmful chemicals from entering the body. They recommend finding options in the local grocery store that are grown with approved substances.

Much of the program is about learning to understand a person’s body. When dieting, prepackaged meals or shakes can be detrimental to a body that doesn’t react well to them. With NutriMost, the person is learning the right types of foods and includes a scan to find out what foods are best for weight loss.

While the program advocates more vegetables, it also helps the person understand what kinds of fruits and vegetables contain good sugars. Once a person understands their body as well as the right sugars and the right foods, NutriMost claims they will lose up to 40 pounds in 40 days.

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Leaders in Medical Advantage Plans: InnovaCare

Medicare Advantage plans, also known as Medicare Private Health plans provide more benefits than that of original Medicare does. Medicare Advantage plans have a contract With the federal government. This allows for payment to be a fixed amount per person to provide extra Medicare benefits.

The most common types of Medicare Advantage plans are with Health Maintenance Organizations, Preferred Provider Organizations, and Private Fee for Service according to Rick Shinto. There are of course more, but these are the most popular. with Medicare Advantage plans, additional benefits may include routine vision or dental care. If you are enrolled in a Medicare Advantage plan, then remember that you do still have Medicare. With a Medicare Advantage plan, you will still pay for your monthly part B premium. If you have a part A premium, you will still be required to pay that monthly as well. Every Medicare Advantage plan must offer and provide all part A and part B services. These are services that were offered by original Medicare. Medicare Advantage can, however, change the rules that determine how you receive care. This can include costs and restrictions. Understanding your Medicare advantage is important to ensure that you are getting all the benefits and best coverage that is available to you.

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Qualifying for a Medicare Advantage plan is not as hard as you may think. If you have Medicare Advantage part A and part B or if you live in a plan’s service area then you qualify. Something that can disqualify you is if you have end-stage renal disease. Although specific plans like the special needs plan can accommodate for this.

InnovaCare Healthcare provides and delivers managed health care services. They provide two convenient ways of health care. One of those includes Medicare advantage. InnovaCare offers quality health care that is sustainable and costs effective. With advanced technology, InnovaCare is able to deliver healthcare that is redefined in today’s complex health care environment.

InnovaCare Health believes that patients come first and that their patients should get quality medical care. InnovaCare differs from other Medicare Advantage plans in that they have a strong patient to provider relationship that makes for innovative practices and a stellar network of professionals according to Penelope Kokkinides. InnovaCare is the leading provider of healthcare that not only meets a person’s needs but also their emotional health and well-being.

Learn more about InnovaCare Health: